Cellular Retirement

Is the cure for cancer… the bench team?! This is Sandra Tsing Loh with the Loh Down on Science. Immunotherapy rallies our defenses against tumors. But sometimes, the defense gets… tired. Older cells release inflammatory signals that weaken immune response. Can we replace them with a “second string?” Get in

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Pain Vibe Check

Got an ‘owwie?’ Could be worse! This is Sandra Tsing Loh with the Loh Down on Science. Healing a bruise is no fun. But what if we could dial down the pain? Meet Tregs — an immune cell and zen master. They normally tell overactive immune responses like aches and

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Insulin Infiltration

Hey diabetics! Imagine ditching the daily needle routine! This is Sandra Tsing Loh with the Loh Down on Science. In Type 1 diabetes, our body’s defenses accidentally wipe out our insulin-making cells. Doctors try swapping in donated cells, but those get smoked too! S-O-S! Save Our Cells! Enter Per-Ola Carlsson’s

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Low Battery Brain

Can we recharge our brains’ batteries? Literally?! This is Sandra Tsing Loh with the Loh Down on Science. Alzheimer’s seems to drain our brains. Some say the disease’s sticky plaques are what causes memory loss. How? Enter Bruce Yankner and team at Harvard. They wondered if the plaques are actually

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Malaria Buzzkill

Do we need to start vaccinating… bugs?! This is Sandra Tsing Loh with the Loh Down on Science… And we’re talking about taking malaria OUT of mosquitoes. Enter Alexandra Probst and her team at Harvard. After screening dozens of antimalarial drugs, they found two that could do the trick. They’re

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Knee-d for Speed

Got one foot stuck in the dial-up era? This is Sandra Tsing Loh with the Loh Down on Science. Current prosthetics are like flip phones – clunky, slow, and plasticky. What’s the next big thing? Ask Hugh Herr and team from MIT! Old prosthetic legs are socket based. Herr’s version?

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The Derm-inator

Is that a new freckle… or something more? This is Sandra Tsing Loh with the Loh Down on Science. Ever spot a weird mole and tumble down a rabbit hole of self-diagnosis? What if your phone could offer a real second opinion, minus the drama? Meet Siyuan Yan and team

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Couch to Clinic

Is the cure for cancer… a jog? This is Sandra Tsing Loh with the Loh Down on Science. Run for your health, they say. But can you outrun… a tumor? Enter Catherine Phelps from the University of Pittsburgh. Her team studied melanoma-prone mice. Some exercised, others stayed sedentary. Surprisingly, tumor

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Outwitting the Scale

Pop til you drop… weight?! This is Sandra Tsing Loh with the Loh Down on Science. Medicines like Ozempic melt the pounds away! But here’s the catch: almost HALF of what’s lost could be muscle. That’s an ancient survival trick — our bodies shed muscle when food is scarce. Can

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Cancer Gender Gap

Zombie outbreak! Who ya gonna call? Mommy?! This is Sandra Tsing Loh with the Loh Down on Science. “Zombie” immune cells have been discovered that let tumors grow unchecked! But only in men’s bladders. How can we stop them? Qingchen Zhu from the Chinese Academy of Sciences went with a

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